Bromopinacolone → HCID 178488979, compound

HRID 1194426Notes

Reaction equation

HRID 1194426 reaction equation
[Br:1][CH2:2][C:3](=[O:8])[C:4]([CH3:7])([CH3:6])[CH3:5].[CH:9](=[N:16][N:17]1[CH:21]=[CH:20][N:19]=[C:18]1[C:22]1[CH:27]=[CH:26][C:25]([O:28][CH3:29])=[CH:24][CH:23]=1)[C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1>C(#N)C>[Br-:1].[CH:9](=[N:16][N+:17]1[CH:21]=[CH:20][N:19]([CH2:2][C:3](=[O:8])[C:4]([CH3:7])([CH3:6])[CH3:5])[C:18]=1[C:22]1[CH:23]=[CH:24][C:25]([O:28][CH3:29])=[CH:26][CH:27]=1)[C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1

Participants

4

Reactant 2

HCID 21642BromopinacoloneHCID 542714701-(Benzylideneamino)-2-(p-methoxyphenyl)imidazole

Product 1

HCID 178488979HCID 178488979, compound

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

3.73 g of 1-bromo-3,3-dimethyl-2-butanone are added to a solution of 4.6 g of 1-(benzylideneamino)-2-(p-methoxyphenyl)imidazole in 250 ml of absolute acetonitrile. After stirring at 60° for 24 hours, the solution is evaporated and the residue is crystallized from ethanol/ether. There is obtained 1-(benzylideneamino)-2-(p-methoxyphenyl)-3-(pivaloylmethyl)imidazolium bromide of melting point 244°.

Workup

  1. customthe solution is evaporated
  2. customthe residue is crystallized from ethanol/ether

Sources & evidence

ORD record
ord-9de5f1e32b974622b30a713da0b7cd42
Source dataset
uspto-grants-1989_03
Patent number
US04814332

Reaction notes

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