HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Anhydride → N-acetyl-N-ethyl-1-[1-(3,4-dichlorophenyl)cyclobutyl]ethylamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | N-ethyl-1-[1-(3,4-dichlorophenyl)cyclobutyl]ethylamine | HCID 13083300 | — |
| Reactant | N-ethyl-1-[1-(3,4-dichlorophenyl)cyclobutyl]ethylamine hydrochloride | HCID 13083301 | — |
| Product | N-acetyl-N-ethyl-1-[1-(3,4-dichlorophenyl)cyclobutyl]ethylamine | HCID 21270245 | — |
Reaction Steps
A mixture of N-ethyl-1-[1(3,4-dichlorophenyl)cyclobutyl]ethylamine (0.5 g prepared by treating the product of Example 21 with aqueous sodium hydroxide) and acetic anhydride (1 ml) was heated at 40°-45° C. for thirty minutes. The reaction mixture was basified and extracted with ether. The ether extract was washed, dried and evaporated to give N-acetyl-N-ethyl-1-[1-(3,4-dichlorophenyl)cyclobutyl]ethylamine as an oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04814352 |
| Source dataset | uspto-grants-1989_03 |
| ORD ID | ord-8b04854c10e7437cae9b7960f5c59f51 |
| Source note | uspto-grants-1989_03 |