Acetic Acid → HCID 356361, compound

Participants

Reaction Steps

As example 39, but using 7-hydroxy-8-methyl-3-(4-chlorophenyl)-4H-1-benzopyran-4-one (1.2 g) instead of 6,7-dihydroxy-3(3-methylphenyl)-4H-1-benzopyran-4-one. Tetrahydrofuran and acetic acid are used instead of dioxan/ethanol and sulphuric acid. The resulting oil is finally purified by elution on a silica gel column (CHCl3) to yield 3,4-dihydro-7-hydroxy-8-methyl-3-(4-chlorophenyl)-2H-1-benzopyran, m.p. 98°-100°.

Provenance & Evidence