反应详情

There was added 30 ml of 30 w/v % aqueous solution of trimethylamine to 11.05 g of (R)-3-chloro-1,2-propanediol (optical purity: 100% e.e., chemical purity: 99%). After reacting for 2 hours at room temperature, the reaction mixture was concentrated. After dissolving the concentrate in 30 ml of thermal ethanol, the solution was stored over night in a refrigerator. Thus, 15.26 g of (S)-2,3-dihydroxypropyltrimethylammonium chloride was obtained.

1. concentrationthe reaction mixture was concentrated
2. dissolutionAfter dissolving the
3. concentrationconcentrate in 30 ml of thermal ethanol
4. waitthe solution was stored over night in a refrigerator