Ammonia → HCID 178512887, compound

HRID 1194653Notes

Reaction equation

HRID 1194653 reaction equation
[NH2:1][C@H:2]([C:7]([NH:9][C@H:10]([C:16]([NH:18][C@H:19]([C:22]([NH:24][C@H:25]([C:33](OC)=[O:34])[CH2:26][CH2:27][CH2:28][NH:29][C:30](=[NH:32])[NH2:31])=[O:23])[CH2:20][OH:21])=[O:17])[CH2:11][CH2:12][CH2:13][CH2:14][NH2:15])=[O:8])[CH2:3][C:4](=[O:6])[OH:5].[NH3:37]>CO>[NH2:1][C@H:2]([C:7]([NH:9][C@H:10]([C:16]([NH:18][C@H:19]([C:22]([NH:24][C@H:25]([C:33]([NH2:37])=[O:34])[CH2:26][CH2:27][CH2:28][NH:29][C:30](=[NH:32])[NH2:31])=[O:23])[CH2:20][OH:21])=[O:17])[CH2:11][CH2:12][CH2:13][CH2:14][NH2:15])=[O:8])[CH2:3][C:4](=[O:6])[OH:5]

Participants

4

Reactant 2

HCID 222AmmoniaHCID 178501455HCID 178501455, compound

Product 1

HCID 178512887HCID 178512887, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Asp-Lys-Ser-Arg-OMe is treated with a saturated solution of ammonia in methanol at room temperature for 2 days. The solvent is removed in vacuo to afford Asp-Lys-Ser-Arg-NH2.

Workup

  1. customThe solvent is removed in vacuo

Sources & evidence

ORD record
ord-cf8d4d76e81943b5b44d84a73b90ecd4
Source dataset
uspto-grants-1989_03
Patent number
US04816449

Reaction notes

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