HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrazine hydrate (1:1) → HCID 135976168, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrazine hydrate (1:1) | HCID 24654 | — |
| Reactant | HCID 86742832 | HCID 86742832 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 135976168 | HCID 135976168 | — |
Reaction Steps
7.0 g (0.03 mole) of 4-(3-(indolyl)-4-oxo-3-methylbutyric acid and 1.7 ml (0.035 mole) of hydrazine hydrate are heated under reflux in 60 ml of ethanol for 2 hours. After the mixture has been concentrated, the residue is chromatographed over a silica gel column with methylene chloride:methanol=9:1 as the eluant and the product is recrystallised from isopropanol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04816454 |
| Source dataset | uspto-grants-1989_03 |
| ORD ID | ord-9cab915d577248148758a1524ef21d60 |
| Source note | uspto-grants-1989_03 |