Pyridine → HCID 19932564, compound

Participants

Reaction Steps

3-[1-(3-amino-phenyl)-1,4-dihydro-[1]-benzothiopyrano[4,3-c]pyrazol-3-yl]-2-cyano-3-oxo-N-phenyl-propanamide (1.9 g) dissolved in dimethylformamide (25 ml) is reacted with acetic anhydride (5 ml) in the presence of pyridine (5 ml) at room temperature for 20 hours. The reaction mixture is diluted with ice water and the precipitate is filtered and washed with water: crystallization from dimethylformamide-ethanol gives 1.6 g of 3-[1-(3-acetylamino-)phenyl)-1,4-dihydro-[1]-benzothiopyrano[4,3-c]pyrazol-3-yl]-2-cyano-3-oxo-N-phenyl-propanamide.

Provenance & Evidence