Phenyl isocyanate → HCID 54112624, compound

HRID 1194826Notes

Reaction equation

HRID 1194826 reaction equation
[CH3:1][CH:2]([CH3:16])[CH2:3][CH2:4][CH:5]([OH:15])[C:6](=[N:13][OH:14])[C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1.[C:17]1([N:23]=[C:24]=[O:25])[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1>C1(C)C=CC=CC=1>[C:17]1([NH:23][C:24]([O:14][N:13]=[C:6]([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=2)[CH:5]([OH:15])[CH2:4][CH2:3][CH:2]([CH3:16])[CH3:1])=[O:25])[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1

Participants

4

Reactant 2

HCID 7672Phenyl isocyanateHCID 86742840HCID 86742840, compound

Product 1

HCID 54112624HCID 54112624, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

2.2 g (0.01 Mol) of 5-methyl-2-hydroxy-caprophenone-oxime are dissolved in 25 ml of toluene and may be slightly heated in this process. Then 1.2 g (0.01 Mol) of phenylisocyanate are added, with the mixture being swirled. The mixture is allowed to stay for one hour, before the solvent is evaporated under vacuum conditions causing crystallisation of residue. Colourless crystals, between 117° C. and 120° C. in flash point, are obtained by recrystallisation from ethanol or ethanol/water.

Workup

  1. temperaturemay be slightly heated in this process
  2. customis evaporated under vacuum conditions
  3. customcrystallisation of residue
  4. customColourless crystals, between 117° C. and 120° C. in flash point, are obtained by recrystallisation from ethanol or ethanol/water

Sources & evidence

ORD record
ord-cd7ba50b80854607881f9bf200c27789
Source dataset
uspto-grants-1989_03
Patent number
US04816487

Reaction notes

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