4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzene-1-sulfonamide → 3'-(8-Methyl-4-oxo-7-trifluoromethyl-4,5-dihydro-3H-benzo[b][1,4]diazepin-2-yl)-biphenyl-4-sulfonic acid amide

HRID 119485Notes

Reaction equation

HRID 119485 reaction equation
[Br:1][c:2]1[cH:3][c:4]([C:8]2=[N:9][c:10]3[c:11]([cH:16][c:17]([C:21]([F:22])([F:23])[F:24])[c:18]([CH3:20])[cH:19]3)[NH:12][C:13](=[O:15])[CH2:14]2)[cH:5][cH:6][cH:7]1.[CH3:25][C:26]1([CH3:27])[C:28]([CH3:29])([CH3:30])[O:31][B:32]([c:33]2[cH:34][cH:35][c:36]([S:39](=[O:40])(=[O:41])[NH2:42])[cH:37][cH:38]2)[O:43]1>>[c:2]1(-[c:33]2[cH:34][cH:35][c:36]([S:39](=[O:40])(=[O:41])[NH2:42])[cH:37][cH:38]2)[cH:3][c:4]([C:8]2=[N:9][c:10]3[c:11]([cH:16][c:17]([C:21]([F:22])([F:23])[F:24])[c:18]([CH3:20])[cH:19]3)[NH:12][C:13](=[O:15])[CH2:14]2)[cH:5][cH:6][cH:7]1

Participants

3

Reactant 2

HCID 164141904-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzene-1-sulfonamideHCID 673614604-(3-Bromo-phenyl)-7-methyl-8-trifluoromethyl-1,3-dihydro-benzo[b][1,4]diazepin-2-one

Product 1

HCID 250521603'-(8-Methyl-4-oxo-7-trifluoromethyl-4,5-dihydro-3H-benzo[b][1,4]diazepin-2-yl)-biphenyl-4-sulfonic acid amide

Sources & evidence

ORD record
ord-97ccfe6c16a74693bec1d13630731300
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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