Thiourea → HCID 14865016, compound

Participants

Reaction Steps

Ethyl 4-bromo-(Z)-2-(cycloheptyloxyimino)-3-oxobutyrate (6.3 g) was treated with thiourea as described in Example 4d. Crystallisation from dichloromethane/hexane gave the title compound as a white solid (4.1 g, 69%), m.p. 107°-8° C. (Found: C: 54.24, H: 6.72, N: 13.33. C14H21N3O3S requires C: 54.00, H: 6.80, N:13.49%). νmax (KBr) 3433, 2930, 1723, 1611, 1540 cm -1 ; δH (CDCl3) 1.33 (3H, t) 1.4-2.0 (12H, m), 4.35 (3H, q+m) 5.60 (2H, br s, exch. D2O), 6.64 (1H,ss).

Provenance & Evidence