N,N-Dimethylaniline → HCID 88627047, compound

Participants

Reaction Steps

Ethyl 4-bromo-(Z)-2-(trans-2-methylcyclohexyl-oxyimino)-3-oxobutyrate (2.5 g) was treated with thiourea (0.57 g) and N,N-dimethylaniline (0.95 ml) as described in Example 4d to give the title compound as a yellow gum (1.07 g) after silica gel chromatography. (Found: M+, 311.1297. C14H21N3O3S requires M, 311.1305); νmax (CH2Cl2) 3475, 3380, 1735, 1600 and 1525 cm-1 ; δH (CDCl3) 0.98 (3H, d, J 6 Hz), 1.35 (3H, t, J 7 Hz), ca 1.1-2.4 (9H, m), 3.84 (1H, m), 4.40 (2H, q, J 7 Hz), 5.88 (2H, broad s), 6.71 (1H, s).

Provenance & Evidence