HCID 140352863, compound → HCID 13826582, compound

HRID 1194908Notes

Reaction equation

HRID 1194908 reaction equation
[CH3:1][C:2]([C:48]([O:50][CH2:51][C:52]1[CH:57]=[CH:56][C:55]([N+:58]([O-:60])=[O:59])=[CH:54][CH:53]=1)=[O:49])([O:4]/[N:5]=[C:6](/[C:23]1[N:24]=[C:25]([NH:28]C(C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)[S:26][CH:27]=1)\[C:7]([O:9]C(C1C=CC=CC=1)C1C=CC=CC=1)=[O:8])[CH3:3]>C(O)=O>[NH2:28][C:25]1[S:26][CH:27]=[C:23](/[C:6](=[N:5]/[O:4][C:2]([CH3:3])([C:48]([O:50][CH2:51][C:52]2[CH:53]=[CH:54][C:55]([N+:58]([O-:60])=[O:59])=[CH:56][CH:57]=2)=[O:49])[CH3:1])/[C:7]([OH:9])=[O:8])[N:24]=1

Participants

3

Reactant 1

HCID 140352863HCID 140352863, compound

Product 1

HCID 13826582HCID 13826582, compound

Reagents, catalysts & solvents 1

HCID 284Formic AcidSolvent

Procedure

Diphenylmethyl (Z)-2-[1-methyl-1-(4-nitrobenzyloxy-carbonyl)ethoxyimino]-2-(2-tritylaminothiazol-4-yl)-acetate (1.0 g) was treated with formic acid under the conditions described in Example 23d. The title compound was obtained as a white solid (0.355 g, 75%); νmax (Nujol) 3300 (br), 3100 (br), 1740, 1625 (br). 1610, 1520, and 1350 cm-1 ; δH ((CD3)2SO) 1.50 (6H, s), 5.30 (2H, s), 6.74 (1H, s), 7.15-7.40 (3H, m), and 7.59 and 8.08 (4H, ABq, J 9 Hz).

Sources & evidence

ORD record
ord-c80c8fcd857646c08a574e69e73a56db
Source dataset
uspto-grants-1989_03
Patent number
US04816452

Reaction notes

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