HCID 154041575, compound → HCID 13577867, compound

HRID 1194909Notes

Reaction equation

HRID 1194909 reaction equation
[N+:1]([C:4]1[CH:58]=[CH:57][C:7]([CH2:8][O:9][C:10]([CH2:12][O:13]/[N:14]=[C:15](/[C:32]2[N:33]=[C:34]([NH:37]C(C3C=CC=CC=3)(C3C=CC=CC=3)C3C=CC=CC=3)[S:35][CH:36]=2)\[C:16]([O:18]C(C2C=CC=CC=2)C2C=CC=CC=2)=[O:17])=[O:11])=[CH:6][CH:5]=1)([O-:3])=[O:2]>C(O)=O>[NH2:37][C:34]1[S:35][CH:36]=[C:32](/[C:15](=[N:14]/[O:13][CH2:12][C:10]([O:9][CH2:8][C:7]2[CH:57]=[CH:58][C:4]([N+:1]([O-:3])=[O:2])=[CH:5][CH:6]=2)=[O:11])/[C:16]([OH:18])=[O:17])[N:33]=1

Participants

3

Reactant 1

HCID 154041575HCID 154041575, compound

Product 1

HCID 13577867HCID 13577867, compound

Reagents, catalysts & solvents 1

HCID 284Formic AcidSolvent

Procedure

Diphenylmethyl (Z)-2-(4-nitrobenzyloxycarbonyl)methoxyimino-2-(2-tritylaminothiazol-4-yl)acetate (2.5 g) was treated with formic acid under the conditions described in Example 23d, increasing the reaction time to 26 h. The title compound was obtained as a white solid (1.13 g); νmax (Nujol) 3520, 1745, 1605, and 1510 cm-1 ; δH ((CD3)2SO) inter alia 4.85 (2H, s), 5.37 (2H, s), 6.86 (1H, s), 7.23 (2H, br. s), 7.57 and 8.23 (4H, ABq, J 8 Hz).

Workup

  1. temperatureincreasing the reaction time to 26 h

Sources & evidence

ORD record
ord-346a8e7ffc24403db37c34b173e71837
Source dataset
uspto-grants-1989_03
Patent number
US04816452

Reaction notes

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