N,N-Dimethylaniline → HCID 88627012, compound

Participants

Reaction Steps

Ethyl 4-bromo-(Z)-2-(trans-2-methoxycyclohexyloxyimino)-3-oxobutyrate was treated with thiourea (0.79 g) and N,N-dimethylaniline (1.318 ml) as described in Example 4d to give the title compound as an orange gum (1.78 g) after silica gel chromatography. νmax (CH2Cl2) 3460, 3370, 3250, 3100, 1730, 1605, and 1530 cm-1 ; δH (CDCl3) inter alia 1.10-1.20 (11H, m), 3.32 (1H, m), 3.43 (3H, s), 4.00-4.50 (3H, m), 6.55 (2H, br. s), and 6.66 (1H, s). [Mass spectrum: EI M+ (327)].

Provenance & Evidence