trans-2-Methylcyclohexanol → ethyl (2Z)-2-[(1R,2S)-2-methylcyclohexyl]oxyimino-3-oxobutanoate

Participants

Reaction Steps

Ethyl (Z)-2-hydroxyimino-3-oxobutyrate (3.48 g) was reacted with trans-2-methylcyclohexanol as described in Example 4a, method 3 to give the title compound (0.476 g, 8.5%), as a colourless liquid, νmax (film) 2930, 1740 and 1690 cm-1, δH (CDCl3) 0.95 (3H, d, J 6.9 Hz), 1.34 (3H, t), 1.3-2.1 (9H, m), 2.40 (3H, s), 4.36 (2H, q), and 4.39 (1H, m).

Provenance & Evidence