Bromine → HCID 88627616, compound

Participants

Reaction Steps

Ethyl (Z)-2-(decahydronaphth-2-yloxyimino)-3-oxobutyrate (1.7 g) in carbon tetrachloride (10 ml) was treated with bromine (0.29 ml). The mixture was stirred at room temperature for lh, then the solvent was evaporated under reduced pressure. The residue was dissolved in ether, washed with water, dried (MgSO4) and evaporated under reduced pressure. The title compound (0.7 g) was isolated by flash chromatography on silica eluting with chloroform:carbon tetrachloride. δH (CDCl3) 1.33 (3H, t), 1.10-2.00 (16H, m), 6.35 (2H, s), 4.40 (2H, q), and 4.40 (1H, m).

Provenance & Evidence