Potassium Bromide → HCID 140352841, compound

Participants

Reaction Steps

Ethyl (Z)-2-(4-methylenecyclohexyloxyimino)-2-(2-tritylaminothiazol-4-yl)acetate (171 mg) was subjected to formic acid deprotection as in Example 1a, but with a reaction time of 1 h. After chromatography, the title compound was obtained as a white solid (74 mg) (Found M+, 309.1135. C14H19N3O3S requires M, 309.1146)-, νmax (KBr) 1724, 1650 (sh), 1624, 1540, 1461, and 1444 cm-1 ; δH (CDCl3) 1.36 (3H, t, J 7 Hz), 1.83, 2.09 and 2.32 (8H, 3m), 4.40 (2H, q, J 7 Hz), 4.48 (1H, m), 4.64 (2H, s), 5.19 (2H, br s, D2O exch.), and 6.73 (1H, s).

Provenance & Evidence