Glyoxal → delta-Gluconolactone

HRID 1194958Notes

Reaction equation

HRID 1194958 reaction equation
[CH:1]([CH:3]=[O:4])=[O:2]>O>[CH2:3]([OH:4])[C@H:1]1[O:2][C:1](=[O:2])[C@H:3]([OH:4])[C@@H:1]([OH:2])[C@@H:3]1[OH:4]

Participants

3

Reactant 1

HCID 7860Glyoxal

Product 1

HCID 7027delta-Gluconolactone

Reagents, catalysts & solvents 1

HCID 962WaterSolvent2×

Procedure

Example 3 is repeated, except that the glyoxal solution is added dropwise to the mixture in the course of 4 hours and at the same time the water used as solvent and the water formed in the course of the reaction are distilled off azeotropically. 2.5 hours after the addition of glyoxal solution the total amount of water which has been distilled off is 167 g. 101 g are obtained of a solid product in which gluconolactone is not detectable.

Workup

  1. distillationare distilled off azeotropically
  2. addition2.5 hours after the addition of glyoxal solution the total amount of water which
  3. distillationhas been distilled off

Sources & evidence

ORD record
ord-a75f99e9c40c40c48e9ebd421f9ecdae
Source dataset
uspto-grants-1989_03
Patent number
US04816553

Reaction notes

Loading…