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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 11950Generated: October 26, 2026

(4R,9aR)-6-(1-(S)-Hydroxy-ethyl)-4-methyl-3,4,9,9a-tetrahydro-1H-2,4a,5-triaza-fluorene-2-carboxylic acid tert-butyl ester → (4R,9aR)-6-(1-(S)-Methoxy-ethyl)-4-methyl-3,4,9,9a-tetrahydro-1H-2,4a,5-triaza-fluorene-2-carboxylic acid tert-butyl ester

https://huagongshe.com/reaction/11950

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(4R,9aR)-6-(1-(S)-Hydroxy-ethyl)-4-methyl-3,4,9,9a-tetrahydro-1H-2,4a,5-triaza-fluorene-2-carboxylic acid tert-butyl esterHCID 69357459—
Reactant(4R,9aR)-6-(2-hydroxy-ethoxymethyl)-4-methyl-3,4,9,9a-tetrahydro-1H-2,4a,5-triaza-fluorene-2-carboxylic acid tert-butyl esterHCID 69557393—
Product(4R,9aR)-6-(1-(S)-Methoxy-ethyl)-4-methyl-3,4,9,9a-tetrahydro-1H-2,4a,5-triaza-fluorene-2-carboxylic acid tert-butyl esterHCID 69356957—

Reaction Steps

This compound was prepared in analogy to Example 41 intermediate b), from (4R,9aR)-6-(1-(S)-hydroxy-ethyl)-4-methyl-3,4,9,9a-tetrahydro-1H--2,4a,5-triaza-fluorene-2-carboxylic acid tert-butyl ester.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07098337B2
Source datasetuspto-grants-2006_08
ORD IDord-2f7d458084d742abb56d69e5108bda68
Source noteuspto-grants-2006_08