Imidazole → HCID 86742887, compound

HRID 1195021Notes

Reaction equation

HRID 1195021 reaction equation
[NH:1]1[CH:5]=[CH:4][N:3]=[CH:2]1.[C:6]([NH:13][C@H:14]([C:19]([OH:21])=[O:20])[CH2:15][CH:16]([CH3:18])[CH3:17])([O:8][C:9]([CH3:12])([CH3:11])[CH3:10])=[O:7]>>[N-:1]1[CH:5]=[CH:4][N:3]=[CH:2]1.[C:6]([NH:13][C@H:14]([C:19]([OH:21])=[O:20])[CH2:15][CH:16]([CH3:17])[CH3:18])([O:8][C:9]([CH3:11])([CH3:10])[CH3:12])=[O:7]

Participants

3

Reactant 2

HCID 795ImidazoleHCID 83170L-Leucine, N-((1,1-dimethylethoxy)carbonyl)-

Product 1

HCID 86742887HCID 86742887, compound

Procedure

The N-BOC-L-leucine imidazolide was prepared from 136 g of imidazole and 115 g of N-BOC-L-leucine following the method described in paragraph B above. Similarly, the magnesium enolate of methyl acid malonate was prepared from 236 g of methyl acid malonate following the method described in paragraph D above.

Sources & evidence

ORD record
ord-93d1fdf3e0ca459096bf1e892986e782
Source dataset
uspto-grants-1989_03
Patent number
US04816598

Reaction notes

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