Potassium Hydroxide → HCID 12330022, compound

HRID 1195045Notes

Reaction equation

HRID 1195045 reaction equation
[Cl:1][C:2]1[CH:21]=[CH:20][CH:19]=[C:18]([C:22]([O:24]CC)=[O:23])[C:3]=1[CH2:4][O:5][C:6]1[CH:11]=[CH:10][C:9]([CH2:12][C:13]([O:15]CC)=[O:14])=[CH:8][CH:7]=1.[OH-].[K+]>>[C:22]([C:18]1[CH:19]=[CH:20][CH:21]=[C:2]([Cl:1])[C:3]=1[CH2:4][O:5][C:6]1[CH:7]=[CH:8][C:9]([CH2:12][C:13]([OH:15])=[O:14])=[CH:10][CH:11]=1)([OH:24])=[O:23]

Participants

3

Reactant 2

HCID 14797Potassium HydroxideHCID 21269134Ethyl 4-[[2-chloro-6-(ethoxycarbonyl)phenyl]methoxy]benzeneacetate

Product 1

HCID 12330022HCID 12330022, compound

Procedure

Reaction of ethyl 4-(2-chloro-6-ethoxycarbonylbenzyloxy)phenylacetate with potassium hydroxide as described in Example 1c provides 4-(2-carboxy-6-chlorobenzyloxy)phenylacetic acid as a colorless solid, m.p. 171°-173° C.

Sources & evidence

ORD record
ord-57048c34b5d94efb9c11e20d7562ccf1
Source dataset
uspto-grants-1989_03
Patent number
US04816591

Reaction notes

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