Thionyl Chloride → HCID 54298241, compound

HRID 1195099Notes

Reaction equation

HRID 1195099 reaction equation
[CH2:1]([O:13][C:14]1[CH:15]=[N:16][C:17]([C:20]2[CH:28]=[CH:27][C:23]([C:24](O)=[O:25])=[CH:22][CH:21]=2)=[N:18][CH:19]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12].S(Cl)([Cl:31])=O>>[CH2:1]([O:13][C:14]1[CH:15]=[N:16][C:17]([C:20]2[CH:28]=[CH:27][C:23]([C:24]([Cl:31])=[O:25])=[CH:22][CH:21]=2)=[N:18][CH:19]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12]

Participants

3

Reactant 2

HCID 24386Thionyl ChlorideHCID 19895119HCID 19895119, compound

Product 1

HCID 54298241HCID 54298241, compound

Procedure

4-(5-n-Dodecyloxypyrimidine-2-yl)benzoic acid (3.0 g) together with excess thionyl chloride were heated for 6 hours under refluxing and thereafter, unaltered thionyl chloride was distilled off to obtain 4-(5-n-dodecyloxypyrimidine-2-yl)phenylcarboxylic acid chloride.

Workup

  1. temperatureunder refluxing
  2. distillationunaltered thionyl chloride was distilled off

Sources & evidence

ORD record
ord-42f09361b0e7495c82bd7541bb5360d2
Source dataset
uspto-grants-1992_05
Patent number
US05110496

Reaction notes

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