Thionyl Chloride → HCID 14848847, compound

HRID 1195103Notes

Reaction equation

HRID 1195103 reaction equation
[CH2:1]([C:11]1[CH:12]=[N:13][C:14]([C:17]2[CH:25]=[CH:24][C:20]([C:21](O)=[O:22])=[CH:19][CH:18]=2)=[N:15][CH:16]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10].S(Cl)([Cl:28])=O>>[CH2:1]([C:11]1[CH:12]=[N:13][C:14]([C:17]2[CH:25]=[CH:24][C:20]([C:21]([Cl:28])=[O:22])=[CH:19][CH:18]=2)=[N:15][CH:16]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10]

Participants

3

Reactant 2

HCID 24386Thionyl ChlorideHCID 146458194-(5-Decylpyrimidin-2-yl)benzoic acid

Product 1

HCID 14848847HCID 14848847, compound

Procedure

4-(5-n-Decylpyrimidine-2-yl)benzoic acid (1.77 g) was heated together with excess thionyl chloride for 8 hours under reflux and thereafter, unaltered thionyl chloride was distilled off to obtain 4-(5-n-decylpyrimidine-2-yl)benzoic acid chloride.

Workup

  1. temperatureunder reflux
  2. distillationunaltered thionyl chloride was distilled off

Sources & evidence

ORD record
ord-7e69692e9c4349b39075e6920a227ef7
Source dataset
uspto-grants-1992_05
Patent number
US05110496

Reaction notes

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