Thionyl Chloride → HCID 54023742, compound

HRID 1195109Notes

Reaction equation

HRID 1195109 reaction equation
[CH2:1]([O:11][C:12]1[CH:13]=[N:14][C:15]([C:18]2[CH:26]=[CH:25][C:21]([C:22](O)=[O:23])=[CH:20][CH:19]=2)=[N:16][CH:17]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10].S(Cl)([Cl:29])=O>>[CH2:1]([O:11][C:12]1[CH:13]=[N:14][C:15]([C:18]2[CH:26]=[CH:25][C:21]([C:22]([Cl:29])=[O:23])=[CH:20][CH:19]=2)=[N:16][CH:17]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10]

Participants

3

Reactant 2

HCID 24386Thionyl ChlorideHCID 18996514HCID 18996514, compound

Product 1

HCID 54023742HCID 54023742, compound

Procedure

4-(5-n-Decyloxypyrimidine-2-yl)benzoic acid (1.50 g) was heated together with excess thionyl chloride for 8 hours under reflux and thereafter, unaltered thionyl chloride was distilled off to obtain 4-(5-n-decyloxypyrimidine-2-yl)benzoic acid chloride.

Workup

  1. temperatureunder reflux
  2. distillationunaltered thionyl chloride was distilled off

Sources & evidence

ORD record
ord-bf2c5b20668049eeb82fcb031f38c48d
Source dataset
uspto-grants-1992_05
Patent number
US05110496

Reaction notes

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