Thionyl Chloride → HCID 54497118, compound

HRID 1195117Notes

Reaction equation

HRID 1195117 reaction equation
[CH2:1]([C:11]1[CH:16]=[CH:15][C:14]([C:17]2[N:22]=[CH:21][C:20]([C:23]([OH:25])=O)=[CH:19][N:18]=2)=[CH:13][CH:12]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10].S(Cl)([Cl:28])=O>>[CH2:1]([C:11]1[CH:16]=[CH:15][C:14]([C:17]2[N:22]=[CH:21][C:20]([C:23]([Cl:28])=[O:25])=[CH:19][N:18]=2)=[CH:13][CH:12]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10]

Participants

3

Reactant 2

HCID 24386Thionyl ChlorideHCID 54405004HCID 54405004, compound

Product 1

HCID 54497118HCID 54497118, compound

Procedure

2-(4-n-Decylphenyl)pyrimidine-5-yl-carboxylic acid (1.5 g) was heated together with excess thionyl chloride for 4 hours under reflux and thereafter, unaltered thionyl chloride was distilled off to obtain 2-(4-n-decylphenyl)pyrimidine-5-yl-carboxylic acid chloride.

Workup

  1. temperatureunder reflux
  2. distillationunaltered thionyl chloride was distilled off

Sources & evidence

ORD record
ord-773456ed4f244020ac76ebe9a222330d
Source dataset
uspto-grants-1992_05
Patent number
US05110496

Reaction notes

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