Ethyl orthoformate → HCID 136186578, compound

HRID 1195145Notes

Reaction equation

HRID 1195145 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([CH:9]=[C:10]([Cl:13])[C:11]=1[OH:12])[C:5]([NH:7][NH2:8])=[O:6].[CH:14](OCC)(OCC)OCC>>[Cl:1][C:2]1[CH:3]=[C:4]([C:5]2[O:6][CH:14]=[N:8][N:7]=2)[CH:9]=[C:10]([Cl:13])[C:11]=1[OH:12]

Participants

3

Reactant 2

HCID 31214Ethyl orthoformateHCID 212211Benzoic acid, 3,5-dichloro-4-hydroxy-, hydrazide

Product 1

HCID 136186578HCID 136186578, compound

Procedure

A mixture of 8.9 g 3,5-dichloro-4-hydroxybenzoic acid hydrazide and 500 ml triethyl orthoformate was stirred and heated at reflux for 4 hrs. The solvent was removed in vacuo to afford the product (9.9 g) as a yellow solid, used directly in the next reaction.

Workup

  1. temperatureheated
  2. temperatureat reflux for 4 hrs
  3. customThe solvent was removed in vacuo

Sources & evidence

ORD record
ord-a2db1fddb0ef41579433a37bc4d73777
Source dataset
uspto-grants-1992_05
Patent number
US05110821

Reaction notes

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