HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → 5-Ethyl-5-(3-azidopropyl)barbituric acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Sodium Azide | HCID 33557 | — |
| Reactant | 5-Ethyl-5-(3-bromopropyl)barbituric acid | HCID 19911801 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | 5-Ethyl-5-(3-azidopropyl)barbituric acid | HCID 19911799 | — |
Reaction Steps
A solution of 30 g of 5-ethyl-5-(3-bromopropyl) barbituric acid and 13 g of sodium azide in 350 ml of acetone was added to 240 ml of water and refluxed for approximately 18 hours. Thereafter, the solution was cooled on ice, filtered, air dried, and dissolved in a minimal amount of hot 95% ethanol. Crystals appeared after cooling and were filtered and air-dried. The melting point was 182°-184° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05110914 |
| Source dataset | uspto-grants-1992_05 |
| ORD ID | ord-1feefcd4bff247e08026f075ee81741d |
| Source note | uspto-grants-1992_05 |