1,3-Cyclopentanedione → HCID 14882925, compound

Participants

Reaction Steps

0.51 g of 4,5-dihydro-6-(4-aminophenyl)-5-methyl-3(2H)-pyridazinone and 0.25 g of cyclopentane-1,3-dione were suspended in a mixture of 5 ml of ethanol and 5 ml of acetic acid and the resulting suspension was refluxed for 7 hours. After cooled, deposited crude crystal was collected by filtrating and recrystallized from DMF-heptane-CHCl3 to give 0.24 g of the title compound. m.p. >300° C. NMR (solvent DMSO-d6 -CDCl3) δ 1.20 (d, 3H), 2.32-3.32 (m, 7H), 5.60 (S, 1H), 7.56 (dd, 4H), 9.82 (S, 1H), 10.80 (S, 1H).

Provenance & Evidence