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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1195235Generated: November 2, 2026

Hydrochloric Acid → Indapamide

https://huagongshe.com/reaction/1195235

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantMethanesulfonateHCID 85257—
Reactant1-Amino-2-methylindolineHCID 169315—
Reactant3-(Aminosulfonyl)-4-chlorobenzoyl chlorideHCID 3017979—
ProductIndapamideHCID 3702—

Reaction Steps

Process according to claim 1, characterised in that the 1-amino-2,3-dihydro-2-methyl-1H-indole is reacted in the form of a hydrochloride or a methanesulphonate with the 4-chloro-3-sulphamoylbenzoyl chloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05110946
Source datasetuspto-grants-1992_05
ORD IDord-0f8a7148371e46c39efe27c9b4b00f1e
Source noteuspto-grants-1992_05