Dimethyl Sulfoxide → HCID 86745743, compound

HRID 1195243Notes

Reaction equation

HRID 1195243 reaction equation
Cl.[CH:2]1([C:5]([C:7]2([CH3:10])[CH2:9][CH2:8]2)=[NH:6])[CH2:4]C1.[Cl:11]([O-:15])(=[O:14])(=[O:13])=[O:12].[NH4+].[CH3:17]S(C)=O>>[Cl:11]([O-:15])(=[O:14])(=[O:13])=[O:12].[NH3+:6][CH:5]1[C:7]2[CH2:9][CH2:8][CH2:17][C:10]=2[CH2:4][CH2:2]1

Participants

4

Reactant 3

HCID 679Dimethyl SulfoxideHCID 24639Ammonium perchlorateHCID 19819014HCID 19819014, compound

Product 1

HCID 86745743HCID 86745743, compoundYield 43%

Conditions

Temperature
100 °C

Procedure

To a solution of 1-cyclopropyl-1-(1-methylcyclopropyl)methanimine hydrochloride (0.060 g, 0.38 mmol) in 0.60 ml of dimethyl sulfoxide was added 0.088 g (0.75 mmol) of ammonium perchlorate. The mixture was heated with stirring at 100° C. for 20 hours. The solvent was distilled out in vacuo and ether was added to the residue. Precipitated crystals was obtained and recrystallized from ethanol to afford 0.36 g (Yield: 43%) of the desired compound.

Workup

  1. temperatureThe mixture was heated
  2. distillationThe solvent was distilled out in vacuo and ether
  3. additionwas added to the residue
  4. customPrecipitated crystals
  5. customwas obtained
  6. customrecrystallized from ethanol

Sources & evidence

ORD record
ord-faae784c562345d58e00a7c07ea2c7c1
Source dataset
uspto-grants-1992_05
Patent number
US05110945

Reaction notes

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