Sodium Hydroxide → HCID 23694526, compound

HRID 1195258Notes

Reaction equation

HRID 1195258 reaction equation
[O:1]1[C:5]2[CH:6]=[CH:7][C:8]([CH:10]([S:14][CH2:15][C:16]([OH:18])=[O:17])[CH2:11][CH2:12][CH3:13])=[CH:9][C:4]=2[O:3][CH2:2]1.[OH-].[Na+:20]>C(O)C>[O:1]1[C:5]2[CH:6]=[CH:7][C:8]([CH:10]([S:14][CH2:15][C:16]([O-:18])=[O:17])[CH2:11][CH2:12][CH3:13])=[CH:9][C:4]=2[O:3][CH2:2]1.[Na+:20]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 14514901HCID 14514901, compound

Product 1

HCID 23694526HCID 23694526, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

100 g of [{1-(1,3-benzodioxol-5-yl)butyl}thio] acetic acid was dissolved in 500 ml of ethanol. 372 ml of 1N-aqueous sodium hydroxide solution was added thereto. Ethanol and water were removed from the reaction mixture by azeotropic distillation and then ether was added to the residue to solidify it. A precipitate thus formed was recovered by filtration and dried to obtain 102 g of the intended compound in the form of a white powder.

Workup

  1. customEthanol and water were removed from the reaction mixture by azeotropic distillation
  2. additionether was added to the residue
  3. customA precipitate thus formed
  4. filtrationwas recovered by filtration
  5. customdried

Sources & evidence

ORD record
ord-8621b2f591614921a0af2b6c47733158
Source dataset
uspto-grants-1992_05
Patent number
US05110956

Reaction notes

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