(Triphenylphosphoranylidene)acetaldehyde → HCID 54457763, compound

HRID 1195329Notes

Reaction equation

HRID 1195329 reaction equation
FC1C=CC(C(C2C=CC(F)=CC=2)=[C:9](C2N(C)N=NN=2)[CH:10]=[O:11])=CC=1.[F:25][C:26]1[CH:31]=[CH:30][C:29]([C:32]([C:42]2[CH:47]=[CH:46][C:45]([F:48])=[CH:44][CH:43]=2)=[C:33]([C:36]2[N:37]=[N:38][N:39]([CH3:41])[N:40]=2)[CH:34]=O)=[CH:28][CH:27]=1.C1(P(=CC=O)(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1>>[F:48][C:45]1[CH:46]=[CH:47][C:42]([C:32]([C:29]2[CH:28]=[CH:27][C:26]([F:25])=[CH:31][CH:30]=2)=[C:33]([C:36]2[N:37]=[N:38][N:39]([CH3:41])[N:40]=2)[CH:34]=[CH:9][CH:10]=[O:11])=[CH:43][CH:44]=1

Participants

4

Reactant 3

HCID 75051(Triphenylphosphoranylidene)acetaldehydeHCID 14539527HCID 14539527, compoundHCID 14723845HCID 14723845, compound

Product 1

HCID 54457763HCID 54457763, compoundYield 90.5%

Procedure

The general procedure of Example 8 was repeated, except that the 3,3-bis(4-fluorophenyl)-2-(1-methyl-1H-tetrazol-5-yl)-2-propenal utilized therein was replaced by 0.67 g (21.0 mmoles) of 3,3-bis(4-fluorophenyl)-2-(2-methyl-2H-tetrazol-5-yl)-2-propenal [prepared in Example 7]. The reaction was carried out with 0.64 g (21.0 mmoles) of triphenylphosphoranylidene acetaldehyde to yield 0.66 g (90.5%) of the title compound.

Sources & evidence

ORD record
ord-627c3b2327354fe7985e2fde81784306
Source dataset
uspto-grants-1992_05
Patent number
US05110940

Reaction notes

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