HCID 53714844, compound → HCID 54526918, compound

HRID 1195443Notes

Reaction equation

HRID 1195443 reaction equation
[F:1][C:2]1[CH:22]=[CH:21][CH:20]=[C:19]([F:23])[C:3]=1[CH2:4][N:5]1[CH:13]=[N:12][C:11]2[C:6]1=[N:7][C:8](NC)=[N:9][C:10]=2[N:14]([CH3:16])[CH3:15].NC1N=C2C(N=CN2CC2C(F)=CC=CC=2F)=C(N(C)C)N=1.C(NC1N=C2C(N=CN2CC2C(F)=CC=CC=2F)=C(N(C)C)N=1)C.FC1C=CC=C(F)C=1CN1C=NC2C1=NC(NC)=NC=2.FC1C=CC=C(F)C=1CN1C=NC2C1=NC(N(C)C)=NC=2.CN(C1N=C2C(N=CN2CC2C(F)=CC=CC=2F)=C(N(C)C)N=1)C.NC1N=C2C(N=CN2CC2C(F)=CC=CC=2F)=C(NC)N=1.CNC1N=C2C(N=CN2CC2C(F)=CC=CC=2F)=C(NC)N=1.NC1N=C2C(N=CN2CC2C(F)=CC=CC=2F)=C(N)N=1.NC1N=C(NC)N=C2C=1N=CN2CC1C(F)=CC=CC=1F.NC1N=C(N(C)C)N=C2C=1N=CN2CC1C(F)=CC=CC=1F.C(NC1N=C2C(N=CN2CC2C(F)=CC=CC=2F)=C(N)N=1)C.[Cl:263]C1N=C2C(N=CN2CC2C(F)=CC=CC=2F)=CN=1>>[Cl:263][C:8]1[N:7]=[C:6]2[C:11]([N:12]=[CH:13][N:5]2[CH2:4][C:3]2[C:2]([F:1])=[CH:22][CH:21]=[CH:20][C:19]=2[F:23])=[C:10]([N:14]([CH3:16])[CH3:15])[N:9]=1

Participants

14

Reactant 13

HCID 53714844HCID 53714844, compoundHCID 53718085HCID 53718085, compoundHCID 53727282HCID 53727282, compoundHCID 53737863HCID 53737863, compoundHCID 53803375HCID 53803375, compoundHCID 53958576HCID 53958576, compoundHCID 54000213HCID 54000213, compoundHCID 54053692HCID 54053692, compoundHCID 54128136HCID 54128136, compoundHCID 54165971HCID 54165971, compoundHCID 54197811HCID 54197811, compoundHCID 54353173HCID 54353173, compoundHCID 54386821HCID 54386821, compound

Product 1

HCID 54526918HCID 54526918, compound

Procedure

9-(2,6-difluorobenzyl)-6-(N,N-dimethylamino)-2-(N-methylamino)-9H-purine; 2-amino-9-(2,6-difluorobenzyl)-6-(N,N-dimethylamino)-9H-purine; 2-(N-ethylamino)-9-(2,6-difluorobenzyl)-6(N,N-dimethylamino)-9H-purine; 9-(2,6-difluorobenzyl)-2-(N-methylamino)-9H-purine; 9-(2,6-difluorobenzyl)-2-(N,N-dimethylamino)-9H-purine; 2,6-bis(N,N-dimethylamino)-9-(2,6-difluorobenzyl)-9H-purine; 2-amino-9-(2,6-difluorobenzyl)-6-(N-methylamino)-9H-purine; 2,6-bis(N-methylamino)-9-(2,6-difluorobenzyl)-9H-purine; 2,6-diamino-9-(2,6-difluorobenzyl)-9H-purine; 6-amino-9-(2,6-difluorobenzyl)-2-(N-methylamino)-9H-purine; 6-amino-9-(2,6-difluorobenzyl)-2-(N,N-dimethylamino)-9H-purine; 2-(N-ethylamino)-6-amino-9-(2,6-difluorobenzyl)-9H-purine and 2-chloro-9-(2,6-difluorobenzyl)-9H-purine.

Sources & evidence

ORD record
ord-44ce459689654706a9f7073e1ff8326e
Source dataset
uspto-grants-1992_05
Patent number
US05110818

Reaction notes

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