Pyrophosphoric acid → HCID 178520530, compound

Participants

Reaction Steps

6.68 g of 4-bromobutyric acid, 1.86 g of ferrocene, 20 g of pyrophosphoric acid, 20 g of polyphosphoric acid, and 20 ml of di n-butylether were added and stirred while heating at 50° to 60° C. for 3 hours, then poured into water, made to be basic with sodium hydroxide, extracted with methylene chloride, and dried. The unreacted-ferrocene was removed with column chromatography, to obtain 2.75 g of 3-bromopropylferrocenyl ketone presented by the formula (D), in a yield of 82.0%. The proton nuclear magnetic resonance (1H--NMR) spectrum of the product is shown in FIG. 4. The result showed that the resulting product was the desired product (3-bromopropylferrocenyl ketone). ##STR11##

Provenance & Evidence