HuagongsheHuagongshe Chemistry Print Report · For research reference only
Salicylaldehyde → HCID 136460587, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Salicylaldehyde | HCID 6998 | — |
| Reactant | Dicyclohexylamine | HCID 7582 | — |
| Reactant | 7-Amino-3-hydroxymethyl-3-cephem-4-carboxylic Acid | HCID 12905480 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 136460587 | HCID 136460587 | 87.4% |
Reaction Steps
7-Amino-3-hydroxymethyl-3-cephem-4-carboxylic acid (9.21 g) was suspended in water (200 ml) and neutralized to ph 7.5 with dicyclohexylamine (7 g). To the resultant solution was added dropwise salicylaldehyde (5.42 g). After stirring at ambient temperature for 2 hours, the precipitates were collected by filtration and dried to give 7-salicylideneamino-3-hydroxymethyl-3-cephem-4-carboxylic acid dicyclohexylamine salt (17.4 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05110921 |
| Source dataset | uspto-grants-1992_05 |
| ORD ID | ord-b587bbb009e34077b39b5dddae4cfdf8 |
| Source note | uspto-grants-1992_05 |