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1-Chloro-3-methoxypropane → Bis(3-methoxypropyl)methylphosphine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1-Chloro-3-methoxypropane | HCID 118927 | — |
| 反応物 | Dichloromethyl-phosphane | HCID 14511949 | — |
| 反応物 | HCID 178495109 | HCID 178495109 | — |
| 生成物 | Bis(3-methoxypropyl)methylphosphine | HCID 449938 | 68% |
反応手順
3-Methoxypropyl-magnesium chloride was generated from 1 -chloro-3-methoxypropane (10.0 g, 92.0 mmol) and Mg metal (2.26 g, 93.0 mmol) and reacted with dichloromethylphosphine (4.1 ml, 0.46 mmol) according to General Method I. The residue was purified by fractional distillation (bp=110° C. @2.8 mm Hg) affording 5.9 g (68%) of bis(3-methoxypropyl)methylphosphine as a mobile colorless oil. 31 pNMR(Benzene-d6):δ-43.3. MS (HREI) m/z=192.1279 (192.1279 calc'd for C9H21O2P).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05112594 |
| 出典データセット | uspto-grants-1992_05 |
| ORD ID | ord-59e07cb8aefc44ac9e84dea751a34122 |
| 出典メモ | uspto-grants-1992_05 |