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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1195693Generated: October 30, 2026

8-Methoxyquinolin-5-amine → HCID 20079050, compound

https://huagongshe.com/reaction/1195693

Reaction equation

Participants

RoleNameHCIDCharge
Reactant8-Methoxyquinolin-5-amineHCID 589466—
Reactant4-(3-Chloro-2-hydroxypropyl)-1-diphenylmethylpiperazineHCID 10360175—
ProductHCID 20079050HCID 2007905011.6%

Reaction Steps

Following the same procedure as in Example 27, reaction and treatment were carried out using 1.81 g of 5-amino-8-methoxyquinoline and 1.23 g of 4-(3-chloro-2-hydroxypropyl)-1-diphenylmethylpiperazine to obtain 200 mg of 5-[3-(4-diphenylmethylpiperazine-1-yl)-2-hydroxy-propylamino]-8-methoxyquinoline.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05112817
Source datasetuspto-grants-1992_05
ORD IDord-7e4b2d507c6c4142bcb825ab803a1cb0
Source noteuspto-grants-1992_05