1,4-Dibromobutane → HCID 20079017, compound

HRID 1195697Notes

Reaction equation

HRID 1195697 reaction equation
[OH:1][C:2]1[CH:11]=[CH:10][CH:9]=[C:8]2[C:3]=1[CH:4]=[CH:5][CH:6]=[N:7]2.[Br:12][CH2:13][CH2:14][CH2:15][CH2:16]Br>>[Br:12][CH2:13][CH2:14][CH2:15][CH2:16][O:1][C:2]1[CH:11]=[CH:10][CH:9]=[C:8]2[C:3]=1[CH:4]=[CH:5][CH:6]=[N:7]2

Participants

3

Reactant 2

HCID 80561,4-DibromobutaneHCID 135441757Quinolin-5-ol

Product 1

HCID 20079017HCID 20079017, compoundYield 40.4%

Procedure

Following the same procedure as in Example 32-(a), reaction and treatment were carried out using 1.0 g of 5-hydroxyquinoline and 2.3 g of 1,4-dibromobutane to obtain 0.78 g of 5-(4-bromobutoxy)quinoline. Furthermore, the same procedure as in Example 32-(b) was repeated with the exception that 0.78 g of N-diphenylmethylpiperazine was used, in order to perform reaction and treatment, so that 0.8 g of the desired compound was obtained.

Workup

  1. customas in Example 32-(a), reaction and treatment

Sources & evidence

ORD record
ord-d75737acdfb948bfa8dbebde14cd97c7
Source dataset
uspto-grants-1992_05
Patent number
US05112817

Reaction notes

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