HCID 796577, compound → HCID 20079082, compound

HRID 1195705Notes

Reaction equation

[F:1][C:2]([F:16])([F:15])[C:3]1[CH:12]=[C:11]([CH3:13])[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][C:9]=2[OH:14])[N:4]=1.[C:17]1([CH:23]([C:32]2[CH:37]=[CH:36][CH:35]=[CH:34][CH:33]=2)[C:24]([N:26]2[CH2:31][CH2:30][NH:29][CH2:28][CH2:27]2)=[O:25])[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1>>[F:16][C:2]([F:1])([F:15])[C:3]1[CH:12]=[C:11]([CH3:13])[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][C:9]=2[O:14][CH2:8][CH:9]([OH:14])[CH2:10][N:29]2[CH2:28][CH2:27][N:26]([C:24](=[O:25])[CH:23]([C:17]3[CH:18]=[CH:19][CH:20]=[CH:21][CH:22]=3)[C:32]3[CH:37]=[CH:36][CH:35]=[CH:34][CH:33]=3)[CH2:31][CH2:30]2)[N:4]=1

Participants

Reactant 2

HCID 796577HCID 796577, compound

HCID 136070691HCID 136070691, compound

Product 1

HCID 20079082HCID 20079082, compound

Procedure

Following the same procedures as in Example 1-(a) and (b), reaction and treatment were carried out using 2-trifluoromethyl-4-methyl-5-hydroxyquinoline prepared in Example 54 and N-(α,α-diphenylacetyl)piperazine in order to obtain the desired compound.

Sources & evidence

ORD record: ord-598089e18f3840ccbf534318abfe280d
Source dataset: uspto-grants-1992_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05112817

Reaction notes

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