3-Formyl-2-methyl-8-nitro-imidazo[1,2-a]pyridine → HCID 21873989, compound

HRID 1195739Notes

Reaction equation

HRID 1195739 reaction equation
[CH:1]([C:3]1[N:7]2[CH:8]=[CH:9][CH:10]=[C:11]([N+:12]([O-])=O)[C:6]2=[N:5][C:4]=1[CH3:15])=[O:2]>CO.[Pd]>[NH2:12][C:11]1[C:6]2[N:7]([C:3]([CH:1]=[O:2])=[C:4]([CH3:15])[N:5]=2)[CH:8]=[CH:9][CH:10]=1

Participants

4

Reactant 1

HCID 541686243-Formyl-2-methyl-8-nitro-imidazo[1,2-a]pyridine

Product 1

HCID 21873989HCID 21873989, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

0.5 g 3-formyl-2-methyl-8-nitro-imidazo[1,2-a]pyridine, dissolved in 200 ml methanol, is hydrogenated after addition of a catalytic amount& of a commercial Pd/C-catalyst at room temperature at low pressure for 11/2 hours.

Sources & evidence

ORD record
ord-66c131d8c25c4b9face4b5edc9704f73
Source dataset
uspto-grants-1992_05
Patent number
US05112834

Reaction notes

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