Water → HCID 178517449, compound

HRID 1195794Notes

Reaction equation

HRID 1195794 reaction equation
[S:1]([CH2:4][C:5]([C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1)=O)[C:2]#[N:3].O.S(=O)(=O)(O)[OH:15]>C(O)(=O)C>[OH:15][C:2]1[S:1][CH:4]=[C:5]([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=2)[N:3]=1

Participants

5

Reactant 3

HCID 962WaterHCID 1118Sulfuric AcidHCID 219693Phenacyl thiocyanate

Product 1

HCID 178517449HCID 178517449, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

Following the known process [Bull. Soc. Chem. France, 11, 2498 (1963)], 8.85 g (50 mmol) of α-thiocyanoacetophenone, 5 ml, of water and 1.3 ml of concentrated sulfuric acid were added to 40 ml of acetic acid and the resultant mixture was refluxed for 2 hours. The reaction mixture was then allowed to stand overnight at room temperature. Precipitated crystals were collected by filtration and then washed with water, whereby the title compound was obtained a colorless crystals.

Workup

  1. customPrecipitated crystals
  2. filtrationwere collected by filtration
  3. washwashed with water, whereby the title compound
  4. customwas obtained a colorless crystals

Sources & evidence

ORD record
ord-25b346935638422f961fcb2edf117d7e
Source dataset
uspto-grants-1992_05
Patent number
US05112841

Reaction notes

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