Ethanol → HCID 54155343, compound

HRID 1195831Notes

Reaction equation

HRID 1195831 reaction equation
[CH3:1][NH:2][CH2:3][C:4]1[C:13]2[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=2)[CH:7]=[CH:6][CH:5]=1.[CH2:14]([OH:16])[CH3:15].[CH2:17]=O>ClCCl>[CH2:14]([O:16][CH2:1][N:2]([CH2:3][C:4]1[C:13]2[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=2)[CH:7]=[CH:6][CH:5]=1)[CH3:17])[CH3:15]

Participants

5

Reactant 3

HCID 702EthanolHCID 712FormaldehydeHCID 84474N-Methyl-N-naphthylmethylamine

Product 1

HCID 54155343HCID 54155343, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

21 g of N-methyl-1-naphthylmethylamine and 9 g of abs. ethanol are treated under ice-cooling in portions with 3.6 g of paraformaldehyde and the mixture stirred for 1 hour at room temperature. The reaction mixture is treated with dichloromethane, filtered and concentrated. The pure product is obtained as a pale yellow oil following vacuum distillation (1.3 mbar/135°-138°).

Workup

  1. filtrationfiltered
  2. concentrationconcentrated
  3. customThe pure product is obtained as a pale yellow oil
  4. distillationvacuum distillation (1.3 mbar/135°-138°)

Sources & evidence

ORD record
ord-be2cdb2c7991437886b7d411e010c973
Source dataset
uspto-grants-1992_05
Patent number
US05112851

Reaction notes

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