HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → 1-(3,4-Dimethoxy-6-nitrobenzoyl)-4-cyclohexylcarbonyl piperidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 4,5-Dimethoxy-2-nitrobenzoic acid | HCID 78690 | — |
| Reactant | 4-Cyclohexylcarbonylpiperidine | HCID 5246602 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 1-(3,4-Dimethoxy-6-nitrobenzoyl)-4-cyclohexylcarbonyl piperidine | HCID 19389218 | — |
Reaction Steps
10.3 g of 3,4-dimethoxy-6-nitrobenzoic acid was converted to the corresponding acid chloride as described in Example 43. It was added to a solution containing 8.83 g of 4-cyclohexylcarbonylpiperidine and 4.58 g of triethylamine in 300 ml of dichloromethane. Yield 16.4 g (90%), m.p. 120°-125° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05112861 |
| Source dataset | uspto-grants-1992_05 |
| ORD ID | ord-437dfe39a9c84fb5bfa499c0652fe18c |
| Source note | uspto-grants-1992_05 |