HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl Acrylate → N-[2-(chroman-3-yl)ethyl]-N,N-bis(2-methoxycarbonylethyl)-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl Acrylate | HCID 7294 | — |
| Reactant | 2-(3,4-dihydro-2H-1-benzopyran-3-yl)ethan-1-amine | HCID 14838408 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | N-[2-(chroman-3-yl)ethyl]-N,N-bis(2-methoxycarbonylethyl)-amine | HCID 14838409 | 100% |
Reaction Steps
6.63 g (77 mmol) of acrylic acid methyl ester are added at room temperature to a solution of 6.2 g (35 mmol) of 3-(2-aminoethyl)chroman in 50 ml of methanol and the whole is stirred for 16 hours at room temperature. The reaction mixture is then concentrated by evaporation in vacuo and yields 12.23 g (100%) of N-[2-(chroman-3-yl)ethyl]-N,N-bis(2-methoxycarbonylethyl)-amine in the form of a reddish oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05112855 |
| Source dataset | uspto-grants-1992_05 |
| ORD ID | ord-532cd69ca068407094ac5cacdf17f38e |
| Source note | uspto-grants-1992_05 |