Hydrazine hydrate (1:1) → HCID 22055164, compound

Participants

Reaction Steps

N,N-Dimethyl N-(11-phthalimidoundecyl)amine (22.9 g) (Example 11) was added to hydrazine hydrate (3.54 g) in ethanol (200 ml), and refluxed for 7 hours. The solvent was removed leaving a white solid, which was partially dissolved in dilute hydrochloric acid and filtered. The pH of the filtrate was adjusted to pH 14 using NaOH (1M) whereupon a brown oil separated from the aqueous phase and was extracted with ether. The organic extract was dried and evaporated to give N,N-dimethyl-N-(11-aminoundecyl)-amine as a brown oil (9.5 g).

Provenance & Evidence