Ethyl Lactate → HCID 10057851, compound

HRID 1196084Notes

Reaction equation

HRID 1196084 reaction equation
C([O:3][C:4](=[O:8])[CH:5]([CH3:7])[OH:6])C.[CH2:9]([CH:11]1[O:13][CH2:12]1)Cl.B(F)(F)F.CC[O:20]CC>>[OH:13][CH:11]([CH2:9][OH:20])[CH2:12][O:6][CH:5]([CH3:7])[C:4]([OH:3])=[O:8]

Participants

4

Reactant 3

HCID 7344Ethyl LactateHCID 7835EpichlorohydrinHCID 8000Boron trifluoride etherate

Product 1

HCID 10057851HCID 10057851, compound

Procedure

177 g of lactic acid ethylester and 46.2 g of epichlorohydrin are admixed by stirring in the presence of 0.5 ml of borontrifluorideetherate during 4 hours at 80° C. The excess of lactic acid ethyl ester is then distilled off with vacuum (20 mm Hg). The residue is dehalogenated and saponified with diluted sodiumhydroxide.

Workup

  1. distillationThe excess of lactic acid ethyl ester is then distilled off with vacuum (20 mm Hg)

Sources & evidence

ORD record
ord-810e445450dd41b3b54c9b8a45730695
Source dataset
uspto-grants-1992_05
Patent number
US05112940

Reaction notes

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