HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzyl Bromide → HCID 10469057, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzyl Bromide | HCID 7498 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | HCID 10352983 | HCID 10352983 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 10469057 | HCID 10469057 | 109.9% |
Reaction Steps
A mixture of 5-(1-hydroxycyclohexyl)-2-methoxy pyridine (26.3 g), benzyl bromide (21.7 g) and potassium carbonate (35 g) was heated in 500 mL of refluxing acetonitrile for 17 hours. The mixture was cooled and filtered, and the solids were washed with methanol. The filtrate was concentrated to give 39.5 g of an oil. HPLC on silica gel (elution with ethyl acetate) afforded 20.8 g of solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05112981 |
| Source dataset | uspto-grants-1992_05 |
| ORD ID | ord-30d7055434464fdba761aeb0c6511369 |
| Source note | uspto-grants-1992_05 |