HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 19768450, compound → HCID 14989568, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 19768450 | HCID 19768450 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 14989568 | HCID 14989568 | 27.1% |
Reaction Steps
A solution of N-[1-[6-(benzoyloxy)-3-pyridinyl]cyclohexyl]benzamide hydrochloride (10.4 g) was heated in 75 ml of refluxing methanol for 1 hour. The solution was cooled, and the solvent was removed in vacuo. The residual oil was triturated with a mixture of ethyl acetate and hexanes, affording 5.9 g of crude product as a solid. Recrystallization from isopropyl alcohol gave 1.91 g of a flocculent solid, m.p. 223°-224° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05112981 |
| Source dataset | uspto-grants-1992_05 |
| ORD ID | ord-ff13a754fb0d478788d78ed0dcc43970 |
| Source note | uspto-grants-1992_05 |