Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | (+-)-2-Butanol | HCID 6568 | — |
| Reactant | Cesium carbonate | HCID 10796 | — |
| Reactant | 2-Fluorotetracene-5,12-dione | HCID 20089828 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 20089833 | HCID 20089833 | 63% |
Reaction Steps
10 g (0.036 mol) of 2-fluoro-5,12-naphthacenequinone, 26 g (0.028 mol) of Cs2CO3 and 10.41 g (0.14 mol) of 3-butanol are introduced into 200 ml of DMF under nitrogen. The reaction mixture is heated to 125° C. and stirred for 41/2 h. After precipitation in 4000 ml of water containing hydrochloric acid, the product is filtered off (crude yield 94%). Chromatography on silica gel (CH2Cl2) gives 63% pure product; melting point 149° C. The procedure in Examples 25-27 is analogous (see Table 2).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05112977 |
|---|
| Source dataset | uspto-grants-1992_05 |
|---|
| ORD ID | ord-313ca6cf456943e18dd860f8d583f123 |
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| Source note | uspto-grants-1992_05 |
|---|
