HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(morpholin-4-ylmethyl)-3,4-dihydro-2H-1,4-benzoxazine → HCID 53942973, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(morpholin-4-ylmethyl)-3,4-dihydro-2H-1,4-benzoxazine | HCID 650697 | — |
| Reactant | Sodium Nitrite | HCID 23668193 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 53942973 | HCID 53942973 | — |
Reaction Steps
Similarly 10.9 g (0.047 mole) of racemic 3-(4-morpholinylmethyl)-3,4-dihydro-2H-1,4-benzoxazine in 250 ml of 2N aqueous hydrochloric acid was treated with 3.9 g (0.057 mole) of sodium nitrite in 50 ml of water at 0° C. to produce racemic 3-(4-morpholinylmethyl)-4-nitroso-3,4-dihydro-2H-1,4-benzoxazine, which was used as such in the next synthetic step without further purification or characterization.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05112820 |
| Source dataset | uspto-grants-1992_05 |
| ORD ID | ord-8598f1d0a6ac4ecf8bc27d396ad7694f |
| Source note | uspto-grants-1992_05 |